lumcThe Leiden University Medical Centre (LUMC) is one of the few academic medical centres in the Netherlands whose core activities include fundamental research. The interaction between fundamental research and patient care forms the basis of its success. LUMC has a major scientific role as a tester of new and existing medical technologies. The LUMC is one of the leading stem cell transplantation centres in the Netherlands and serves a European function with respect to island cell transplantation, solid organ transplantation and mesenchymal stem cell transplantation. The LUMC was awarded special government funding to develop regenerative medicine. LUMC has a strong record on MSC research encompassing the complete area of basic, preclinical and translational research and performance of clinical trials and holds licenses for harvesting, manipulating and exporting (stem) cell products. Since 2004, LUMC has been producing MSC products for clinical trial use and has been executing more than 10 single- and multi-centre studies (phase 1,2 and 3) with these products, also in international collaborations with partners in and outside Europe.