Productive NEPHSTROM meeting at Leiden

The NEPHSTROM consortium enjoyed a constructive meeting at the end of May, hosted by Prof. Wim Fibbe and his team at theLeiden University Medical Centre in Leiden. Over the course of the two day meeting, progress was reviewed, plans were refined and preparations for the next six months of collaboration were made.

The photo shows the consortium in the University of Leiden’s historic Pieterskerkplein.

NEPHSTROM Leiden Meeting

 

NEPHSTROM registered on ClinicalTrials.gov

The NEPHSTROM project has registered its clinical trial on the open-access public clinical trials repository, ClinicalTrials.gov. This is an important step, and ensures that any scientist or member of the public can identity NEPHSTROM and its aims, approach and results. This is valuable for researchers who want to review all trials in a particular disease, or using a particular type of therapy. See the online information here

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Excellent project meeting at Bergamo

The consortium enjoyed a constructive meeting at the end of November, hosted by Prof Beppe Remuzzi and his team at the Insitute Mario Negri in Bergamo. Progress was reviewed, plans were refined and preparations for the next six months of collaboration were made.

The photo shows the consortium at the Institute Mario Negri.

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NEPHSTROM in the Media again

NEPHSTROM partner NHSBT received good coverage in the UK and international diabetes media in October.

Diabetes breakthrough: New stem cells that can halt kidney disease about to be tested
express.co.uk, 19 Oct 2015, UK, Keyword: NHS Blood and Transplant, Journalist: Jon Austin
Dr Eric Austin, head of Stem Cell Immunotherapy at the Advanced Therapy Unit within the Stem Cells and Immunotherapies department at NHS Blood and Transplant’s site in Speke, Liverpool, said: “This is an exciting project for us to be involved with – especially as the treatment has the potential to lead to life saving outcomes for a major illness.

Also reported in:Screenshot 2015-11-18 18.59.03

STEM CELLS TRIAL TO HELP DIABETES PATIENTS WITH KIDNEY DISEASE
PA News Wire, 20 Oct 2015

The project also enjoyed coverage in

  • The Diabetes Times
  • Diabetes.co.uk
  • Diabetes Forum.com
  • StarMine News
  • PharmaTimes Digital

Looking forward to Bergamo

This month (November) sees the consortium assemble in Bergamo for our second plenary meeting (the first one since the kick-off in Dublin). The meeting is hosted by Beppe Remuzzi and his team at the Istituto Mario Negri (IRFMN). We look forward to catching up on all the news from the cell production centres, and to putting in place the facilities to carry out the clinical trial (led, of course, by IRFMN).

Bergamo

LMU Munich Press Release

LMUM distributed a press release about NEPHSTROM, aimed at the German-language press and public.

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The full text was as follows:

Neue Klinische Studie zur Stammzelltherapie bei diabetischer Nierenschädigung

24.06.2015 – Die Arbeitsgruppe um Prof. Hans-Joachim Anders am Nephrologischen Zentrum der Medizinischen Klinik und Poliklinik IV leitet ein Teilprojekt in dem EU-Projekt NEPHSTROM (Novel Stromal Cell Therapy for Diabetic Kidney Disease).

Präklinische Arbeiten und eine erste klinische Studie zur Stammzelltherapie bei diabetischer Nierenschädigung werden durch das Horizon-2020-Programm der Europäischen Union mit 6 Millionen Euro gefördert. Das auf vier Jahre ausgelegte Projekt wird die durch Forscher an der National University of Ireland in Galway (NUI Galway) entwickelte Stammzelltherapie auf ihre klinische Sicherheit und Wirksamkeit überprüfen.

Eine diabetische Nephropathie (DN) entwickeln 25 bis 40 Prozent aller Patienten mit Diabetes weltweit, häufig mit der Folge eines Nierenversagens und damit einer wesentlichen Todesursache bei Diabetes. “Wir hoffen, mit einer einmaligen intravenösen Injektion von Mesenchymalen Stammzellen den Verlauf der diabetischen Nierenschädigung günstig beeinflussen zu können”, sagt Prof. Anders, Oberarzt des Nephrologischen Zentrums am LMU-Klinikum.