Entries by nephstrom_admin

NEPHSTROM Clinical Trial Underway at Four Locations

“We are pleased the NEPHSTROM clinical trial has commenced and that randomized diabetic patients with kidney disease whose previous therapies failed now are receiving ORBCEL-M™ immunotherapy,” said Dr Larry Couture, CEO of Orbsen Therapeutics. “The study may be a breakthrough moment for patients with end-stage renal disease caused by diabetes.” Orbsen Therapeutics, a biotechnology company focused […]

Five NEPHSTROM partners to participate in GMP November event in Galway

NEPHSTROM partners from NUI Galway, Orbsen Therapeutics, Leiden University Medical Center, Terumo BCT Europe NV and the NHS Blood and Transport will facilitate sessions at the Center for Cell Manufacturing Ireland’s event “GMP Manufacturing, Scale-Up and Challenges of ATMPs”. This 2-day event will take place on November 14 and 15, 2018 at the National University of […]

New NEPHSTROM study published in the CCLM

A new NEPHSTROM study has just been published in the Clinical Chemistry and Laboratory Medicine (CCLM): “Defining reference intervals for a serum growth differentiation factor-15 (GDF-15) assay in a Caucasian population and its potential utility in diabetic kidney disease (DKD)” by Siobhan M. Hamon, Tomás P. Griffin, Md Nahidul Islam, Deirdre Wall, Matthew D. Griffin, and […]

NEPHSTROM celebrates UK Kidney Week in Harrogate, UK

Prof Paul Cockwell, Consultant Nephrologist of the Queen Elizabeth Hospital Birmingham, UK gave a superb talk about the NEPHSTROM project at the annual conference of the UK Renal Association. The conference was held in Harrogate, England from 19-21 June 2018 during the UK Kidney Week. It was co-organised by the British Renal Society and the Renal Association. Paul’s […]

NEPHSTROM celebrates International Clinical Trials Day with the HRB-TMRN

EU funded projects NEPHSTROM, VISICORT, ADIPOA-2, and AUTOSTEM coordinated by the Regenerative Medicine Institute (REMEDI) at National University of Ireland, Galway exhibited at a unique outreach activity targeted at primary school students. The event called the START competition was the brainchild of the Health Research Board (Ireland)’s Trials Methodology Research Network (HRB-TMRN) in Galway. In celebration of International Clinical Trials Day […]

Nephstrom study published in Immunology & Cell Biology

A National University of Ireland Galway REMEDI-Cúram-NEPHSTROM- funded study ‘Phenotypic and functional heterogeneity of human intermediate monocytes based on HLA-DR expression’ has been recently published in Immunology & Cell Biology. The body of research by Connaughton EP, Naicker S, Hanley SA, Slevin SM, Eykelenboom JK, Lowndes NF, O’Brien T, Ceredig R, Griffin MD, and Dennedy MC was published on 5 March 2018.   Abstract Human […]

NEPHSTROM research published in Frontiers in Immunology

  The paper ‘Anti-Donor Immune Responses Elicited by Allogeneic Mesenchymal Stem Cells and Their Extracellular Vesicles: Are We Still Learning?’ is based on the work of Dr Paul Lohan, Dr Oliver Treacy, Prof Matthew Griffin, Prof Thomas Ritter and Dr Aideen Ryan of the National University of Ireland Galway. The publication appears in the November 24, […]

‘Chronic Kidney Disease’- a new Nature Reviews Disease Primer by NEPHSTROM researchers

Our partner Prof Dr Hans-Achim Anders of Ludwig-Maximilians-Universitaet Muenchen has coordinated a new publication in Nature Reviews ‘Disease Primers’ on Chronic Kidney Disease  (CKD). Contributing authors are Paola Romagnani, Giuseppe Remuzzi, Richard Glassock,  Adeera Levin, Kitty J. Jager, Marcello Tonelli, Ziad Massy, Christoph Wanner and  Hans-Joachim Anders. Abstract:  Chronic kidney disease (CKD) is defined by persistent urine abnormalities, […]

NEPHSTROM meets the masses at Ireland’s largest public science forum hosted by NUI Galway

NEPHSTROM researchers at NUI Galway exhibited at the Galway Science and Technology Forum on 26 November 2017. In excess of 20,000 people attended the exhibition day. The NUI Galway regenerative medicine stand was the brainchild of Dr Siobhán Gaughan who works across several EU-funded stem cell projects coordinated at NUI Galway. Researchers Matthew Griffin, Cathal […]

European Regulators approve NEPHSTROM Clinical Trial of MSC Therapy for Diabetic Kidney Disease

The stromal cell therapy, ORBCEL-M™, developed as part of NEPHSTROM, a European Union Horizon 2020-funded research project, has been approved to begin testing in a randomised, double-blind, and placebo-controlled European clinical trial to treat diabetic kidney disease. Orbsen’s ORBCEL-M™, a novel highly purified positively-selected stromal cell therapy for diabetic kidney disease, has demonstrated significant improvements […]